The histopathology of mice in each group. Histopathological findings in dorsal skin from BLM-induced scleroderma mice treated with etretinate (b), peanut oil (c), and without agents (d) for 28 days, and mice that finished the BLM treatment (a). Dermal thickness of mice treated with etretinate thinned compared to the other group.Biopsied specimens were stained by haematoxylin and eosin. Original magnification: ×40.